The Effect of Chronic IL-18 exposure on Innate Lymphoid Cell.

Chronic excess IL-18 has ben well associated with autoimmune disease like SJIA, particularity the development of Macrophage Activation Syndrome. Children who are diagnosed with these diseases are known to often have dysregulation of their cytotoxic cells: CD8+ T cells, Natural Killer cells Innate Lymphoid Cells. In my project we want to understand the effect what…